Hotel Principe Eugenio is in Rome's historic centre, between the basilicas of Santa Maria Maggiore and San Giovanni in Laterano. There is free Wi-Fi in the rooms and lobby. The Principe Eugenio is on the first floor of a building of the early 20th century. Vittorio Emanuele Metro Station, line A, is 100 metres from the hotel. Nearby Piazza Vittorio, as the Romans call it, is home to a nice park. Nearby there is one of Rome's largest indoor markets.

The hotel has spacious rooms: singles, doubles and triples. All rooms have private bathroom with complimentary toiletries and hairdryer, air conditioning, mini fridge, wireless, electronic safe, satellite TV, direct dial telephone and central heated and. Some rooms have a terrace.